Cell Reprogramming for Aging

As we age, the brain gets less efficient and forgetfulness increases by leaps and bounds. Acquiring Alzheimer’s disease or Parkinsonism is not the case always but certain other degenerative proteins cite actions that decrease the brain efficiency. It is the cholinergic and dopaminergic neurons that begin the deleterious effect on the memory. Since the cholinergic neurotransmitters govern the actions at the basal ganglia of the brain, the neurodegenerative changes through normal aging begin their action.

Along with aging, the brain cells start being damaged and give rise to various mental disorders. No such medication has been invented that may completely cure the following ailments but delay the process. Similarly, aging can never be stopped but the consequences can be slowed down.

In the article Gene Therapy and Cell Reprogramming For the Aging Brain: Achievements and Promise the author has discussed aging and the effects of cholinergic and dopaminergic agonists and antagonists in a vast perspective. The article also features modification of cells with age and the mal-effects on diabetic patients. The journal Current Gene Therapy focuses on the gene and cell therapy. Moreover, the research tells much about the experimental evidence supporting the neuroprotective relevance of these and related factors in the aging brain.

Hepatitis and Interferon

Hepatitis is a viral disease that remains in the body for longer durations and even lifetime, depending upon the viral genotype.  It exists as Hepatitis A, B, C, D, E, G and H. Hepatitis B and C are treated by interferon at variant doses in every individual. There is a slight chance from recovery from Hepatitis B but it has a vaccine. Hepatitis C is treatable yet chances of recurrence are strong because it does not have a vaccine.

Interferon has a binding affinity with the cellular proteins that in turns kills the viruses despite of their various shapes which may not be identified otherwise. The Pharmacokinetics and Pharmacodynamics of Interferon was studied with and without combination of ribavirin, administered between the range of 800g – 1400g thrice a week or daily. Sustained Virologic Response (SVR) and Rapid Virologic Response (RVR) exposure- response were modeled using logistic regression. The author of the article Population Pharmacokinetics and Pharmacodynamics of Albinterferon Alfa-2b in Patients Treated for Hepatitis C Virus Genotype 2/3 has detailed review on the genotype research and a comparison of efficacy of combined or individual regimens.

Also, Bentham Science Publishers has much more details on the viral hepatitis topics in their open access journals.

The Impact Of Sleep Apnea On Human Health:

Majority of people experience snoring issues while sleeping. In some cases, it can occur due to nasal blockages which result into oral grunts and groans. Similarly, some people suffer from breathing impairments or occasional exchange of gases during sleep. This is known as Sleep Apnea. "Sleep apnea is a common disease that has a powerful impact on public health because it greatly increases the risk of strokes, cancers and mortality from any cause," said lead author Nathaniel S. Marshall, PhD, senior lecturer in clinical trials at the University of Sydney in Australia.

“Sleep Apnea is a common diseasethat has a powerful impact on public health because it greatly increases therisk of strokes, cancers and mortality from any cause.” (Nathaniel S. Marshall, PhD, Senior Lecturer in Clinical Trials at the University of Sydney, Australia)

"Sleep apnea is a common disease that has a powerful impact on public health because it greatly increases the risk of strokes, cancers and mortality from any cause," said lead author Nathaniel S. Marshall, PhD, senior lecturer in clinical trials at the University of Sydney in Australia."Sleep apnea is a common disease that has a powerful impact on public health because it greatly increases the risk of strokes, cancers and mortality from any cause," said lead author Nathaniel S. Marshall, PhD, senior lecturer in clinical trials at the University of Sydney in Australia."Sleep apnea is a common disease that has a powerful impact on public health because it greatly increases the risk of strokes, cancers and mortality from any cause," said lead author Nathaniel S. Marshall, PhD, senior lecturer in clinical trials at the University of Sydney in Australia."Sleep apnea is a common disease that has a powerful impact on public health because it greatly increases the risk of strokes, cancers and mortality from any cause," said lead author Nathaniel S. Marshall, PhD, senior lecturer in clinical trials at the University of Sydney in Australia.Sleep Apnea can be classified into three types:

Ø  Obstructive Sleep Apnea (OSA)

Ø  Central Sleep Apnea (CSA)

Ø  Complex Sleep Apnea (Amalgamation of the above two)

The OSA can take place due to a physical obstruction in the respiratory tract, whereas, the main cause of CSA is the lack of respiratory effort. The combination of both of them is reported in a limited number of cases.

Despite of the fact that Sleep Apnea can happen to any age group or gender, this condition is more common in females. One of the Bentham Science Publishers articles “Influence of Gender on C-Reactive Protein, Fibrinogen, and Erythrocyte Sedimentation Rate in Obstructive Sleep Apnea.” covers all the details related to protein bindings with fibrinogens and erythrocytes sedimentation rates. This research also provides ample information explaining the systemic inflammatory markers relating it with female physiological activity which supports OSA more in females than males.

Cat Bite- A source of bacteria and several infections

Cat Bites are more serious and dangerous as compared to a dog bite. The research analysis has shown that 1 out of 3 patients wounded by cat bites died in hospital while two third of them had to go through surgical treatment.

This is because of the fact that the cats usually carry various types of bacteria in their mouth which causes infection in tissues, resulting into blood poisoning, also known as septicemia. The most common symptoms of these wound fissures at an early stage include flu and fever and under rare circumstances can lead to patient`s death if the medical treatment is not taken out at the appropriate time.

Several safety measures should be taken in the above case in order to prevent the infection from spreading to surrounding tissues and joints. Cleaning the wound is the first and prime requirement, but scrubbing should be avoided. It is also important to control and stop bleeding by seeking medical attention through a physician.

Bentham Science Publishers is a remarkable name in the STM publishing industry. There are a number of Bentham publications on infection and infectious diseases, such as Anti-Infective Agents, Infectious Disorders-Drug Targets and Recent Patents on Anti-Infective Drug Discovery. For further details, visit:

http://benthamscience.com/journal/browse-by-title.php?alphacode=A&pcount=1

Heavy Drinking:

The intake of excessive drinking can result in accelerated memory loss as well as mental decay. Premature Old Age can also be a symptom of heavy drinking.

Men who consume more than two alcoholic drinks per day during their middle age may speed up the process of memory loss and premature old age up to six years.

Research has deduced that middle-aged men are at higher risk of mental decay, because they are involved in heavy drinking for many years.

Bentham Science Publishers is one of the leading STM publishing companies of the industry. It publishes more than 116 online and print journals and more than 300 eBooks. One of its journals is “Current drug Abuse Reviews.” Current Drug Abuse Reviews aim to publish the highest quality reviews, meta-analyses and drug clinical trial studies on all latest advances on alcohol and drug abuse and addiction.

Google Lenses for Diabetes

For diabetic patients tired with having to use pin prick blood tests every now and then to monitor their blood sugar levels, the good news is that Google has invented a novel pair of contact lenses to keep their glucose levels in check. These contacts come fitted with special sensors, minute transistors and a tiny hair-thin antenna to observe the sugar levels through the tears of the diabetes patient. The readings are then wirelessly transmitted to a handheld monitor device.

Unmanageable blood sugar levels in diabetic patients are hazardous to health and more often than not lead to kidney, eyes and heart problems. Many patients have to administer pin pricks, sometimes more than 10 times in a single day in order to keep an eye on their glucose levels, as is evident from the case of Michael Vahradian, who finds it rather cumbersome to use them. Google lens, which will be available in markets in about 5 years, will revolutionize the way diabetes blood sugar levels are monitored and will ease the process for millions around the world.

Google is best known as a search engine and advertising company. However, it has launched a number of other useful wearable products, like Google Glass and a special pair of glasses fitted with cameras and a small computer display. Although, research on contact lenses for monitoring blood sugar levels started many years ago at the University of Washington, it was Google really which made the project a reality. The man behind the invention, Brian Otis expresses his opinion:

“You can take it to a certain level in an academic setting, but at Google we were given the latitude to invest in this project.”

The Chairperson of the board of the American Diabetes Association is pleased with the efforts of the researchers and scientists who are working tirelessly to come up with novel and better solutions for patients suffering from diabetes. Readers can refer to Current Diabetes Reviews by Bentham Science Publishers for the latest developments in the field of diabetes and its cures. A Bentham eBook, Epidemiology of Type 2 Diabetes is also a useful guide on diabetes epidemiology.

Bentham Science e-books: Orthodontic Treatment of Class III Malocclusion:

Bentham Science presents numerous eBooks that covers all major fields of natural science, technology, humanities and medicine. Bentham e-book offers authors flexible publication solutions. These electronic books are rapidly published using state-of-the-art internet technology.

Orthodontic Treatment of Class III Malocclusion is a clinical textbook which highlights both research findings as well as clinical treatment of patients with Class III malocclusions. The volume equips readers with a critical review of present information about the craniofacial biology behind various treatment strategies, diagnosis and treatment planning in both growing and non-growing Class III patients and contemporary orthodontic appliances using implants and miniscrews.

The book is divided into sections proving evidence-based research on the genetic and epigenetic factors, contemporary diagnosis and treatment planning for patients, early treatment of class III problems, treatment of class III problems in the adolescents, surgical treatment of adult class III patients and treatment of class III problems in patients with craniofacial anomalies.

This book will empower clinicians with a sound knowledge about rationale for using certain treatment modalities and will help both general practitioners and specialists such as pediatric dentists and orthodontists to use this information for their daily practice.

To read full review, you can visit:

http://benthamscience.com/ebooks/9781608054916/index.htm

Introducing Bentham Science Publisher’s YouTube Channel

Bentham Science Publishers publishes quality research and scholarly articles with a stringent peer- reviewing process. There are around 116 online and print journals, 150 plus open access journals and a wide range of eBooks.  Moreover, Bentham Science Publishers has a prominent position at all the social media forums with more than 25 pages on Facebook, our hub of all the latest news on Wordpress, as well as onTwitter and LinkedIn. A collection of videos sent by our esteemed authors are also uploaded on our YouTube channel every week.

Bentham Science Publisher’s YouTube channel has more than 20 podcasts uploaded of eBooks and journals, apart from other informative videos.

We are updating podcasts on a regular basis, ensuring maximum exposure. We not only upload eBooks podcasts, but we upload podcasts for journals as well. A journal podcaston titled:“Fish Oil has Beneficial Effects on Behavior Impairment and Oxidative Stress in Rats Subjected to a Hepatic Encephalopathy Model” by Dr. AneteC.Ferraz

Here’s the Abstract:

Hepatic encephalopathy (HE) is a severe neuropsychiatric complication of liver failure, in which there is injury to brain cells, particularly neurons and glia. Brain cells and their function are greatly influenced by omega-3 polyunsaturated fatty acids, essential components of cell membrane phospholipids in the brain that are crucial to normal function. In summary, FO protected against spatial memory deficits and oxidative stress caused by HE in rats subjected to liver lesion due to TAA intoxication. Further studies are necessary to understand the mechanism underlying FO behaviors in rats subjected to encephalopathy.

To watch the podcast for this journal article, please click on the following link: https://www.youtube.com/watch?v=8gcYa7KIquI&list=PLgqAw3jxjphktDoEnZiXlMhadZJc5vA7V&index=5

For latest podcasts on journals and eBooks please subscribe to our YouTube channel: https://www.youtube.com/channel/UCFzSVHgGkjFW2Q8WV8-gzUw/videos?view=1

Speech and Brain Activity:

According to a recent research, it is concluded that speech, head injuries, stroke, brain and communication disorders are treatable as brain covers both sides of the brain. This study reveals that at a time only one side of the brain is used and there is a direct relationship between speech and brain activity.

The researchers focused on various parts of the brain during speech. The participants were asked to repeat non- words like “pob” and “kig.” This experiment brought to light that these non-words trigger brain activities which allowed the researchers to separate speech from language.

The results obtained through this research helped in the better understanding of the speech generation within the brain and also led to innovative techniques for the treatment of speech related disorders.

Bentham Science Publishers is a remarkable name in the STM Publishing industry, having journals and eBooks on various genres including; natural science, information technology, medicine etc. Bentham Science Publishers has an impact factor journal named “Neuroscience and Biomedical Engineering” which can assist researchers for additional research on the subject. 

Hypertension

Hypertension, which is referred to as high blood pressure, is a common condition in which the arteries have constant high blood pressure.  The Blood pressure is basically the force that is pushing up against the vessel walls of blood.

Each time the heart beats, it pushes the blood to the whole body via arteries. The more high the pressure, the tougher the heart has to pump.

Hypertension is a disease which can further lead to damaged organs and various illnesses that include heart failure or stroke. The normal consistent blood pressure level should be 120/80, where 120 signifies systolic pressure (the highest pressure in arteries) whereas 80 symbolizes diastolic (the minimum pressure in the arteries). However, if the blood pressure exceeds from 80/120 to 139/89, then it is called pre-hypertension. If it reaches to 140/90 or more than that, it is considered as high blood pressure or Hypertension.

There are many factors that can be highly linked with this condition which includes; obesity, smoking, diabetes, lack of any physical activity, deficiency of vitamin D, stress, aging and also it comes through genes.

Bentham Science Publishers is a reputable name in the publishing industry, it has more than 160 journals and a variety of eBooks. Current Hypertension Reviews publishes frontier reviews, original research articles and guest edited thematic issues on all the latest advances on hypertension and its related areas e.g. nephrology, clinical care, and therapy. The journal’s aim is to publish the highest quality review articles dedicated to clinical research n the field. The journal is essential for all the clinicians and researchers in the field of hypertension.

For further details about this journal, log on to: http://www.benthamscience.com/journal/aims-scope.php?journalID=chr#top

Current Alzheimer Research:

Alzheimer is a disease which is an intense brain disorder that harms the brain cells and eventually destroys it. This damaging further leads to memory loss and brings about many changes in the functionality of the brain and cognition.

This disease develops gradually and it gets worse as more brain cells die or wither. Unfortunately, Alzheimer is a fatal disease and currently has no successful cure. Researchers have been conducted globally to find the cure of this fatal syndrome.

Current Alzheimer Research – an excellent journal from the shelves of Bentham Science Publishers that features peer-reviewed letter articles, frontier review, and research covering all major areas of Alzheimer disease. This journal has an impact factor 3.676. This multidisciplinary journal will help in understanding the neurobiology, genetics, pathogenesis, and treatment strategies of Alzheimer’s disease.  Stay up to date on the latest advances in the cure, treatment, research and diagnosis of Alzheimer’s disease by visiting: http://www.benthamscience.com/car/

Dyslexia- A Neurological Disorder

Dyslexia is a disorder which is characterized by difficulty in reading and learning. This is a most common learning disorder found in children that hinders the ability of a person to read, learn, spell, write and even sometimes in speaking. This is disease which attacks the kids and is persist throughout the life. To reach the favorable outcomes, treatment must be taken o time because it can get severe. The severity of Dyslexia differs from mild to severe.

Dyslexia in children is caused by the mutilation in the brain’s capability to interpret the images delivered from the eyes and ears into comprehensible language. It is not because of the hearing and vision problems, but it is due to the brain damage, psychological retardation or lack of intellect.

Dyslexia may go undiagnosed in the early years of schooling because the symptoms are vague to determine if it is Dyslexia or a kid is not willing to go to school and is showing signs like these. The common symptoms includes, the reversal of number and letter, difficulty in copying work from the board, difficulty in playing organized games and sports, difficulty of distinguishing left and right. Whereas, the aural problems linked to dyslexia includes, difficulty of remembering what he is hearing, recalling problems, words get funny because they miss parts of words and kipping whole sentences.

Bentham Science Publishers, a reputed name in the industry of publishing has more than 160 journals that serve the scientists all around the world in various fields of science, biotechnology, social sciences and humanities. CNS and Neurological Disorders- Drug Targets;  a journal of Bentham science which is all about neurological disorders. For further details, you can visit: 

http://benthamscience.com/journal/index.php?journalID=cnsnddt

http://benthamscience.com/index.php

What are Immunodeficiency Disorders?

To get a better understanding about immune disorders, you need to know the basics of how exactly immune system works. The immune system consists of various organs including, bone marrow, spleen, lymph nodes and spleen. These organs release lymphocytes that are classified as T cells and B cells.  These cells fight against the antigens such as viruses, bacteria, cancer cells and other harmful body fluids. Both B cells and T cells play their part in fighting off the bacteria out of the body through killing the virus and by producing antibodies.

Immunodeficiency is a disorder that affects the body immune system thus prevents the ability of the body to fight diseases and infections. This disorder makes a person more vulnerable of catching bacterial infections and viruses. Immune disorders are generally acquired or innate. Usually, the acquired immune disorder is characterized as secondary disorder whereas; the congenital immune disorder is called primary.

There are various factors that can make an immune system weak, for instance; the body fluids such as sperm of blood from the body of an individual affected with HIV can cause AIDS. The removal of spleen from your body can lead to a weaker immune system.

The treatment varies according to the condition of individuals. It commonly includes the antibody and antibiotics replacement. There are several drugs that are used to treat the infections caused by this disorder; the drugs must be taken according to the prescription.

Dangers of Carbon Monoxide:

This winter season is seen to be the coldest winter the world has observed after a long period of time. Temperatures in the next few years are also expected to drop more. The people using heaters need to very vigilant because the heaters give off a gas which is commonly known as the silent killer.

Carbon monoxide is present inside offices and houses because of the usage of heaters. It is a colorless and odorless gas with a chemical formula of CO. One might not be aware of its presence and the dangers it causes. The major symptoms of excess intake of CO include nausea and headache which is often misconcepted as a symptom of flu or viral fever.

Continuous exposure of CO can also result into various acute symptoms such as chest pain, vomiting, confusion and serious medical conditions.

Bentham Science Publishers is one of the most remarkable STM Publishers. It publishes over 116 online and print journals and more than 300 e-books. One of the eBooks is “Environmental Issues for the Twenty-First Century and their Impact on Human Health”. This e-book discusses the ecological and health impacts of aquaculture, the Alberta tar sands development, the Gulf Oil disaster of 2010, the hazards of inadequately safeguarding water supplies, and global warming, to name some of the important topics.

An eBook from the Digital Library of Bentham Science: Advances in Genome Science: Probing intracellular regulation (Volume 2):

Bentham Science Publishers is a fast growing international STM publishing company with over 300 eBooks, 116 online and print journals and 230 free to view Open Access online journals.  Their eBooks provide corporate researchers, professionals, academicians, under- graduates and graduates globally with the most current information in their subject areas of interest.

Here is a short review of one of the latest eBooks of Bentham, “Advances in Genome Science: Probing intracellular regulation”-Genome science or genomics is essential to advancing knowledge in the fields of biology and medicine. Specifically, researchers learn about the molecular biology behind the genetic expression in living organisms and related methods of treating human genetic diseases (including gene therapy). Advances in Genome Science, is an e-book series which provides a multi-disciplinary view of some of the latest developments in genome research, allowing readers to capture the essentiality and diversity of genomics.

The second volume of this eBook series contains a selection of articles on intracellular gene regulation and expression in human disease such as arthritis, Alzheimer’s disease, Nijmegen Breakage Syndrome, Tumors and Malaria among other diseases. The volume also features some chapters on plant genetics.

To read more about this eBook, visit:http://www.benthamscience.com/ebooks/9781608057566/index.htm

Breathing Problems: COPD (chronic obstructive pulmonary disease)

COPD is one of the major causes of disability in the United States, and the third largest cause of death as well. There are millions of people who are suffering from this disease. Although, there is a huge percentage of individuals who may have the disease and may not even know about it.

COPD is usually diagnosed in older or middle-aged adults. This disease is not contagious.

COPD (chronic obstructive pulmonary disease) causes difficulty in breathing. COPD has two main types of chronic bronchitis and emphysema.  The cause of COPD is damage to the lungs by air pollution, chemical fumes or dust; however, cigarette smoking is the main reason for COPD. 

Breathing is a process which causes air flow from airways and elastic air sacs. Breathing in causes air sacs to inflate like a small balloon, while breathing out causes them to deflate pushing the air out. In COPD, less air flows in and out of these airways because of inelasticity, wall of air sacs are destroyed, the walls become thick and inflamed, and airways become clogged because of mucus. Due to these reasons it becomes problematic for the patients to breathe.

This disease develops slowly; symptoms often worsen gradually limiting your capacity to perform routine activities. Chronic COPD may even prevent one from doing basic activities like walking, sleeping, or eating. Common symptoms include coughing with mucus, shortness of breath while doing physical activity, wheezing and chest tightness.

Diagnosis of COPD involves lung functions test, imaging test, blood test. COPD has no cure yet; doctors have failed to repair the damage caused to the airways and lungs. Although, certain treatments have shown positive results including medicines, oxygen therapy, surgery or lungs transplant. This disease can be avoided by following a healthy lifestyle and quitting smoking.

Bentham Science aims to publish eBooks in all major areas of technology, social sciences, medicine and humanities. Their eBooks provide professionals, corporate researchers, academicians, graduates and under-graduates globally with the most contemporary information in their subject areas of interest. Bentham Science continues to publish books in every field. A few new eBooks are going to appear under the Bentham Science name, 'Lung Macrophages in Health and Disease'by Sandra Hodge.

The eBook discusses lung’s reaction to injury, the alveolar macrophage, maintenance of lung structure, cancer biology and many more. Along with essentials to understand the development of novel therapeutic approaches for acute and chronic disease.

Middle East Respiratory Syndrome Coronavirus (MERS-CoV)

Middle East respiratory syndrome coronavirus or MERS-CoV is a flu epidemic in the Middle East. This virus is highly contagious and deadly. It is basically an acute respiratory infection presenting as pneumonia.

MERS causes high fever, coughing, and pneumonia in humans. It affects animals as well, which is why it is recommended to avoid having close contact with farm animals and barn areas, where the virus has potentially been circulating.

In the last week of December, a case of an elderly man from Riyadh has been reported to have died from a confirmed MERS case. WHO announced five more people have been diagnosed with this lethal Middle East Respiratory Syndrome virus, bringing to a total of 176 cases, of which 75 have already died.

MERS is spreading gradually; most of the reported cases are in Saudi Arabia, Kuwait, Qatar, Jordan, UAE, France, Oman, Tunisia, Germany, Spain Italy and Britain.

Furthermore, WHO directed general public to adhere to precautionary measures while visiting a barn or farm. Strict hygiene measures should be taken such as washing hands before and after touching the animals, and before eating food. Moreover, contact with sick animals should be avoided at all times.

For further inquiry on the subject, you can read more on the disease and similar virus infections on our website http://www.benthamscience.com/. Bentham Science Publishers is one of the biggest names in the STM industry. The website has latest eBooks and journals ranging from natural science, medicine, to technology. One of its journals is “Infectious Disorders - Drug Targets” which has articles on infectious diseases latest drug discoveries.

Protein & Peptide Letters

Bentham Science Publishers is one of the leading names in STM publishing industry. The company aims to publish eBooks in all major areas of technology, social sciences, medicine and humanities. Their eBooks provide professionals, corporate researchers, academicians, graduates and under-graduates globally with the most contemporary information in their subject areas of interest.

Protein & Peptide Letters publishes letters, original research papers, mini-reviews and guest edited issues in all important aspects of protein and peptide research, including structural studies, advances in recombinant expression, function, synthesis, enzymology, immunology, molecular modeling, and drug design. Manuscripts must have a significant element of novelty, timeliness and urgency that merit rapid publication. Reports of crystallization and preliminary structure determination of biologically important proteins are considered only if they include significant new approaches or deal with proteins of immediate importance, and preliminary structure determinations of biologically important proteins. Purely theoretical/review papers should provide new insight into the principles of protein/peptide structure and function. Manuscripts describing computational work should include some experimental data to provide confirmation of the results of calculations.

For detailed book review, please visit: http://www.benthamscience.com/ppl/index.htm